Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement:
Both are due to a quantitative defect in globin chain synthesis
Thalassemia is due to less synthesis of globin molecules
Sickle cell anemia is due to a quantitative problem of globin molecules
Both are due to a qualitative defect in globin chain synthesis
Thalassemia differs from sickle-cell anaemia in that Thalassemia is a quantitative problem of synthesising too few globin molecules (reduced rate of synthesis), whereas sickle-cell anaemia is a qualitative problem of synthesising an incorrectly functioning globin (due to the substitution of amino acids) .
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