a typical mammalian cell contains approximately 2.2 metres of DNA, which is a length far greater than the dimension of a typical nucleus (approximately 10⁻⁶ m) . This DNA is accommodated through an elaborate packaging process where the negatively charged DNA is wrapped around a positively charged histone octamer to form structures called nucleosomes . These nucleosomes appear as 'beads-on-string' under an electron microscope and are further coiled and condensed to form chromatin fibres and eventually chromosomes . Mastering these molecular packaging concepts is a high-priority strategy, as NCERT textbooks serve as the primary source for approximately 95% of NEET Biology questions .