Which of the following statements are correct regarding skeletal muscle? A: Muscle bundles are held together by collagenous connective tissue layer called fascicle. B: Sarcoplasmic reticulum of muscle fibre is a store house of calcium ions. C: Striated appearance of skeletal muscle fibre is due to distribution pattern of actin and myosin proteins. D: M line is considered as functional unit of contraction called sarcomere. Choose the most appropriate answer from the options given below:
C and D only
A, B and C only
B and C only
A, C and D only
Statement A is incorrect because muscle bundles are themselves called fascicles; they are held together by a collagenous connective tissue layer called fascia. Statement B is correct as the sarcoplasmic reticulum is the storehouse of calcium ions . Statement C is correct because the striated appearance is due to the distribution pattern of actin and myosin proteins . Statement D is incorrect because the functional unit of contraction is the sarcomere, defined as the portion of the myofibril between two successive 'Z' lines , whereas the 'M' line is a thin fibrous membrane holding thick filaments together.
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