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NEET BIOLOGYMedium

Identify the step in tricarboxylic acid cycle, which does not involve oxidation of substrate?

A

Succinic acid

B

Succinyl-CoA

C

Isocitrate

D

Malic acid

Step-by-Step Solution

describing the Tricarboxylic Acid Cycle (Krebs' cycle):

  1. Isocitrate undergoes oxidative decarboxylation to form α\alpha-ketoglutaric acid (producing NADH).
  2. Succinic acid undergoes oxidation to form Fumarate (producing FADH2_2).
  3. Malic acid undergoes oxidation to form Oxaloacetic acid (producing NADH).
  4. The conversion of Succinyl-CoA to Succinic acid involves substrate-level phosphorylation where a molecule of GTP is synthesised. This step does not involve oxidation (removal of hydrogen) of the substrate.
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