gamete formation involves meiosis, and the enzyme recombinase is required during Prophase-I. Specifically, during the pachytene stage of Prophase-I, recombination nodules appear where crossing over occurs between non-sister chromatids of homologous chromosomes . The sources state that crossing over is an enzyme-mediated process, and the enzyme involved is called recombinase . This process leads to the recombination of genetic material, which is completed by the end of the pachytene stage . Understanding these meiotic events is a high-priority strategy for medical aspirants, as NCERT textbooks serve as the primary source for approximately 95% of NEET Biology questions .