Which of the following statements regarding post-transcriptional events in an eukaryotic cell is INCORRECT?
Transport of pre-mRNA to the cytoplasm prior to splicing
Removal of introns and joining of exons
Addition of methyl group at 5' end of hnRNA
Addition of adenine residues at 3' end of hnRNA
According to the textbook, in eukaryotes, the primary transcript (hnRNA) contains both exons and introns and is non-functional. It must undergo processing within the nucleus, which includes splicing (removal of introns and joining of exons), capping (addition of methyl guanosine triphosphate at the 5'-end), and tailing (addition of adenylate residues at the 3'-end). It is the fully processed hnRNA, now called mRNA, that is then transported out of the nucleus for translation . Therefore, transport to the cytoplasm occurs after splicing, not prior to it.
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