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NEET BIOLOGYMedium

Which of the following statements regarding post-transcriptional events in an eukaryotic cell is INCORRECT?

A

Transport of pre-mRNA to the cytoplasm prior to splicing

B

Removal of introns and joining of exons

C

Addition of methyl group at 5' end of hnRNA

D

Addition of adenine residues at 3' end of hnRNA

Step-by-Step Solution

According to the textbook, in eukaryotes, the primary transcript (hnRNA) contains both exons and introns and is non-functional. It must undergo processing within the nucleus, which includes splicing (removal of introns and joining of exons), capping (addition of methyl guanosine triphosphate at the 5'-end), and tailing (addition of adenylate residues at the 3'-end). It is the fully processed hnRNA, now called mRNA, that is then transported out of the nucleus for translation . Therefore, transport to the cytoplasm occurs after splicing, not prior to it.

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