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NEET BIOLOGYMedium

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): In human beings, insulin is synthesized as a pro-hormone which needs to be processed before it becomes fully mature and functional. Reason (R): The extra stretch of C-peptide is to be removed from A and B peptide chain of insulin. In the light of the above statements, Choose the most appropriate answer from the option given below :

A

(A) is True but (R) is False.

B

(A) is False but (R) is True.

C

Both (A) and (R) are True and (R) is the correct explanation of (A).

D

Both (A) and (R) are True but (R) is not the correct explanation of (A).

Step-by-Step Solution

In mammals, including humans, insulin is synthesised as a pro-hormone... which contains an extra stretch called the C peptide. This C peptide is not present in the mature insulin and is removed during maturation into insulin' . The Reason correctly explains that the processing required (Assertion) involves the removal of this specific C-peptide stretch to allow the hormone to become mature and functional.

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