Signals from fully developed foetus and placenta ultimately lead to parturition which requires the release of:
Oxytocin from maternal pituitary
Oxytocin from foetal pituitary
Relaxin from the placenta
Estrogen from placenta
According to the sources, the process of childbirth (parturition) is induced by a complex neuroendocrine mechanism . The signals originate from the fully developed foetus and the placenta, which induce mild uterine contractions known as the foetal ejection reflex . This reflex specifically triggers the release of oxytocin from the maternal pituitary gland . Oxytocin then acts on the uterine muscle to cause stronger contractions, which in turn stimulate further oxytocin secretion in a stimulatory reflex that leads to the expulsion of the baby .
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