Anaphase I of meiosis is specifically characterised by the separation of homologous chromosomes, which move toward opposite poles of the cell . Crucially, during this stage, the sister chromatids remain associated at their centromeres, unlike in mitosis or anaphase II where the centromeres split to allow sister chromatids to separate . This distinction is fundamental to the reduction division process that ensures gametes receive a haploid set of chromosomes . Mastering these precise meiotic events is a high-priority strategy for medical aspirants, as NCERT textbooks serve as the definitive source for approximately 95% of NEET Biology questions .