Q1. Which of the following is an example of a chromosomal disorder caused by trisomy?A. Turner’s syndromeB. Sickle-cell anemiaC. Down’s syndromeD. Phenylketonuria
Q2. Which type of mutation occurs when a single base substitution results in a premature stop codon?A. Missense mutationB. Nonsense mutationC. Silent mutationD. Frameshift mutation
Q3. Which law of inheritance states that alleles segregate independently during gamete formation?A. Law of DominanceB. Law of SegregationC. Law of Independent AssortmentD. Hardy-Weinberg Law
Q4. Which genetic disorder is caused by trisomy of chromosome 21?A. Turner’s syndromeB. Klinefelter’s syndromeC. Down’s syndromeD. Edward’s syndrome
Q5. Which of the following statements about Mendelian inheritance is incorrect?A. Mendel proposed the Law of Segregation and Law of Independent Assortment.B. A monohybrid cross produces a 3:1 phenotypic ratio in the F2 generation.C. Dihybrid crosses result in a 9:3:3:1 phenotypic ratio.D. Mendel's laws apply only to plants and not to animals.
Q6. Which of the following represents a heterozygous genotype for a Mendelian trait?A. AAB. aaC. AaD. AAA
Q7. Which of the following traits in pea plants was NOT studied by Mendel?A. Seed colorB. Pod shapeC. Leaf venationD. Flower position
Q8. Which of the following genetic disorders is incorrectly matched with its cause?A. Down’s syndrome - Trisomy 21B. Turner’s syndrome - 45, XOC. Klinefelter’s syndrome - 47, XYYD. Patau syndrome - Trisomy 13
Q9. Which of the following best describes a test cross?A. A cross between two homozygous individualsB. A cross between an individual of unknown genotype and a homozygous recessive individualC. A cross between two heterozygous individualsD. A cross between two recessive individuals
Q10. Which of the following statements about Mendelian inheritance is incorrect?A. Mendel's experiments were conducted on pea plants.B. The Law of Dominance explains why heterozygous individuals express the dominant trait.C. Dihybrid crosses do not follow the Law of Independent Assortment.D. The Law of Segregation states that allele pairs separate during gamete formation.