Q1. Which of the following is an example of polygenic inheritance?A. HemophiliaB. Sickle-cell anemiaC. Human skin colorD. Cystic fibrosis
Q2. Which of the following is a correct statement about epistasis?A. It occurs when one gene influences multiple traits.B. It follows Mendel’s Law of Independent Assortment.C. One gene masks the effect of another gene.D. Epistasis is the same as pleiotropy.
Q3. Which of the following is an incorrect statement about linkage?A. Linked genes are located close together on the same chromosome.B. Genes far apart on a chromosome assort independently.C. Linked genes always segregate independently.D. Crossing over can break the linkage between genes.
Q4. Which of the following statements about genetic mutations is incorrect?A. Frameshift mutations can be caused by insertions or deletions.B. Silent mutations change the amino acid sequence of a protein.C. Missense mutations result in a single amino acid change.D. Nonsense mutations introduce a premature stop codon.
Q5. Which of the following statements about genes and alleles is incorrect?A. A gene is a segment of DNA that codes for a protein.B. Alleles are different versions of the same gene.C. All genes have only two possible alleles.D. Dominant alleles always express their trait in heterozygous individuals.
Q6. Which disorder is caused due to a defect in the dystrophin gene on the X chromosome?A. Cystic fibrosisB. Duchenne muscular dystrophyC. Huntington’s diseaseD. Sickle-cell anemia
Q7. What is the sex chromosome composition of an individual with Turner’s syndrome?A. 47, XXYB. 45, XOC. 46, XYD. 47, XYY
Q8. Which genetic disorder is caused by an expansion of CAG repeats?A. Sickle-cell anemiaB. Huntington’s diseaseC. HemophiliaD. Cystic fibrosis
Q9. Which of the following is a correct statement about sex-linked inheritance?A. Y-linked traits can be passed to both male and female offspring.B. X-linked recessive disorders are more common in males.C. Females can never be carriers of X-linked disorders.D. X-linked dominant traits only affect males.
Q10. Which of the following is an incorrect statement about linkage?A. Linked genes are located on the same chromosome.B. Crossing over can break the linkage between genes.C. Linked genes always assort independently.D. The closer two genes are, the less likely they are to be separated by crossing over.