back to directory
NEET CHEMISTRYAldehydes, Ketones and Carboxylic AcidsMedium

Question

Reaction of a carbonyl compound with one of the following reagents involves nucleophilic addition followed by the elimination of water. The reagent is:

A

a Grignard reagent

B

hydrazine in presence of feebly acidic solution

C

hydrocyanic acid

D

sodium hydrogen sulphite

Step-by-Step Solution

The reaction of aldehydes and ketones with ammonia derivatives (H2NZH_2N-Z) is a characteristic nucleophilic addition-elimination reaction.

  1. Mechanism: The nitrogen atom of the nucleophile attacks the carbonyl carbon (nucleophilic addition) to form a tetrahedral intermediate. This intermediate then loses a molecule of water (elimination) to form a compound with a >C=NZ>C=N-Z double bond.
  2. Hydrazine: Hydrazine (NH2NH2NH_2NH_2) reacts with carbonyl compounds in a feebly acidic medium to eliminate water and form hydrazones. >C=O+H2NNH2H+>C=NNH2+H2O>C=O + H_2N-NH_2 \xrightarrow{H^+} >C=N-NH_2 + H_2O
  3. Other Options:
  • Grignard reagent: Undergoes nucleophilic addition to form an alkoxide, which yields an alcohol upon hydrolysis (no water elimination in the addition step).
  • Hydrocyanic acid (HCN): Undergoes nucleophilic addition to form cyanohydrins (no water elimination).
  • Sodium hydrogen sulphite: Undergoes nucleophilic addition to form bisulphite addition products (no water elimination).

Exam Context & Concepts Covered

This question aligns with the NEET CHEMISTRY syllabus, specifically targeting concepts from Aldehydes, Ketones and Carboxylic Acids. Mastering this topic is crucial for scoring well in the upcoming medical entrance examinations. Solving conceptually related problems will help you understand the nuances of these concepts and improve your problem-solving speed.

CHEMISTRYAldehydes, Ketones and Carboxylic Acidsreactioncarbonylcompoundfollowingreagents

More Aldehydes, Ketones and Carboxylic Acids Questions

View all

The product formed from the following reaction sequence is:

A.Data Missing
B.Data Missing
C.Data Missing
D.Data Missing
MediumSolve

Which of the chemical reagents can be used to distinguish between cis-cyclopenta-1,2-diol and trans-cyclopenta-1,2-diol?

A.Ozone
B.MnO₂
C.Aluminium isopropoxide
D.Acetone
HardSolve

The product(s) formed from the following reaction is/are:

A.RCOOH only
B.$RCH_2COOH$ only
C.Data Missing
D.RCOOH and $RCH_2COOH$
MediumSolve

The intermediate compound 'X' in the following chemical reaction is: $$\text{Toluene} \xrightarrow{CrO_2Cl_2/CS_2} X \xrightarrow{H_3O^+} \text{Benzaldehyde}$$

A.$$C_6H_5-CH_2Cl$$
B.$$C_6H_5-CHCl_2$$
C.$$C_6H_5-CH(OH)_2$$
D.$$C_6H_5-CH(OCrOHCl_2)_2$$
MediumSolve

The product that cannot be formed in the following reaction is:

A.Data Missing
B.Data Missing
C.4
D.Data Missing
MediumSolve

The correct statement regarding a carbonyl compound with a hydrogen atom on its alpha-carbon is:

A.A carbonyl compound with a hydrogen atom on its alpha-carbon rapidly equilibrates with its corresponding enol and this process is known as aldehyde-ketone equilibration.
B.A carbonyl compound with a hydrogen atom on its alpha-carbon rapidly equilibrates with its corresponding enol and this process is known as carbonylation.
C.A carbonyl compound with a hydrogen atom on its alpha-carbon rapidly equilibrates with its corresponding enol and this process is known as keto-enol tautomerism.
D.A carbonyl compound with a hydrogen atom on its alpha-carbon never equilibrates with its corresponding enol.
EasySolve

The product of the below-mentioned reaction is: (Reaction Scheme Missing)

A.Option 1 (Image Missing)
B.Option 2 (Image Missing)
C.Option 3 (Image Missing)
D.Option 4 (Image Missing)
MediumSolve

$$RMgX + CO_2 \xrightarrow{\text{dry ether}} Y \xrightarrow{H_3O^+} RCOOH$$ What is Y in the above reaction?

A.$(RCOO)_2Mg$
B.$RCOO^-Mg^+X$
C.$R_3CO^-Mg^+X$
D.$RCOO^-X^+$
MediumSolve

This neet chemistry practice question is part of the TopperSquare free question bank. TopperSquare offers 15,000+ chapter-wise NEET MCQs across Physics, Chemistry, and Biology with detailed step-by-step explanations, full mock tests, NEET PYQs (2010–2024), and an AI-powered performance analytics dashboard. browse all neet practice questions → · practice chemistry sets →