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NEET generalGeneralHard

Question

Calcium is important in skeletal muscle contraction because it

1

Detaches the myosin head from the actin filament.

2

Activates the myosin ATPase by binding to it.

3

Binds to troponin to remove the masking of active sites on actin for myosin.

4

Prevents the formation of bonds between the myosin cross bridges and the actin filament.

Step-by-Step Solution

Signal for contraction increase Ca++Ca^{++} level many folds in the sarcoplasm. Ca++Ca^{++} now binds with sub-unit of troponin (troponin "C") which is masking the active site on actin filament and displaces the sub-unit of troponin. Once the active site is exposed, head of the myosin attaches and initiate contraction by sliding the actin over myosin.

Exam Context & Concepts Covered

This question aligns with the NEET general syllabus, specifically targeting concepts from General. Mastering this topic is crucial for scoring well in the upcoming medical entrance examinations. Solving conceptually related problems will help you understand the nuances of these concepts and improve your problem-solving speed.

generalcalciumimportantskeletalmusclecontraction

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