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NEET BIOLOGYPrinciples of Inheritance and VariationMedium

Question

Among fraternal twins, one baby is haemophilic while the baby's brother is normal. Which statement is true?

A

Baby is male

B

Baby is female

C

Mother is heterozygous

D

Mother is homozygous

Step-by-Step Solution

Haemophilia is a sex-linked recessive disease (X-linked) .

  1. Analysis of the Mother: The twins are fraternal (derived from two different eggs). One offspring (the brother) is normal, meaning he received a normal X chromosome () from the mother. The other baby is haemophilic, meaning they received an affected X chromosome () from the mother (if male) or from both parents (if female).
  2. Conclusion: Since the mother possessed both the normal allele (passed to the normal son) and the affected allele (passed to the affected child), she must be heterozygous (a carrier, genotype ).
  3. Other Options: While the affected baby is most likely male (as female haemophiliacs are extremely rare and require an affected father) , the most genetically certain statement based on the segregation of alleles to the twins is the mother's heterozygosity.

Exam Context & Concepts Covered

This question aligns with the NEET BIOLOGY syllabus, specifically targeting concepts from Principles of Inheritance and Variation. Mastering this topic is crucial for scoring well in the upcoming medical entrance examinations. Solving conceptually related problems will help you understand the nuances of these concepts and improve your problem-solving speed.

BIOLOGYPrinciples of Inheritance and Variationfraternalhaemophilicbrothernormalstatement

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