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NEET BIOLOGYPrinciples of Inheritance and VariationMedium

Question

A normal girl, whose mother is haemophilic marries a male with no ancestral history of haemophilia. What will be the possible phenotypes of the offsprings?

A

(a) and (b) only

B

(b) and (c) only

C

(a) and (d) only

D

(b) and (d) only

Step-by-Step Solution

Haemophilia is a sex-linked recessive disorder .

  1. Girl's Genotype: The girl is phenotypically normal but her mother was haemophilic (). Therefore, she must have received the haemophilic allele () from her mother. Her genotype is carrier ().
  2. Husband's Genotype: He has no history of the disease, so he is a normal male ().
  3. Cross: Carrier Female () × Normal Male ().
  4. Offspring:
  • Daughters: (Carrier, normal phenotype) and (Normal). All daughters are phenotypically normal.
  • Sons: (Haemophilic) and (Normal).
  1. Conclusion: The possible phenotypes are Haemophilic sons and Normal offspring (sons and daughters). A haemophilic daughter is impossible in this cross because the father is normal and cannot contribute the required recessive allele . Assuming statements correspond to: (a) Haemophilic daughter (Impossible), (b) Haemophilic son (Possible), (c/d) Normal phenotypes (Possible), the correct combination must exclude (a). Option 4 (b and d) represents the valid phenotypic outcomes for sons (affected and normal).

Exam Context & Concepts Covered

This question aligns with the NEET BIOLOGY syllabus, specifically targeting concepts from Principles of Inheritance and Variation. Mastering this topic is crucial for scoring well in the upcoming medical entrance examinations. Solving conceptually related problems will help you understand the nuances of these concepts and improve your problem-solving speed.

BIOLOGYPrinciples of Inheritance and Variationnormalmotherhaemophilicmarriesancestral

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